EVERYTHING ABOUT ONOLIDINE

Epidural clonidine used as an adjunct to local anesthetics has a few unique mechanisms of action. 1st, the stimulation of alpha-two-receptors in the dorsal horn lowers discomfort transmission. Secondly, clonidine can cause neighborhood vasoconstriction that limits vascular removal of community epidural anesthetics.Clonidine is an extended-expressio